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Mpox Vaccine Cdc

Mpox: What You Need to Know About Vaccination

Why Get Vaccinated Against Mpox?

  • The CDC recommends vaccination against mpox if you have had known or suspected exposure to someone with mpox.
  • Vaccination is an important tool in preventing the spread of mpox.
  • The vaccine may still protect against severe illness, hospitalization, and death.

Available Vaccines

There are two types of vaccines available in the United States that can prevent mpox:
  1. JYNNEOS: A 2-dose vaccine developed to protect against mpox and all other members of that virus family.
  2. ACAM2000: A smallpox vaccine that can also be used to prevent mpox.

Who Should Get Vaccinated?

The Advisory Committee on Immunization Practices (ACIP) recommends that people 18 years and older who are at risk or have been exposed to mpox get vaccinated.

People at risk include those who:

  • Have had close contact with someone with mpox.
  • Are healthcare workers or laboratory personnel who handle mpox specimens.
  • Are gay, bisexual, or other men who have sex with men.

Vaccine Efficacy

The JYNNEOS vaccine is highly effective in preventing mpox. Studies have shown that it is 85% effective in preventing severe mpox infection.

The ACAM2000 vaccine is also effective in preventing mpox, but it can cause more side effects than the JYNNEOS vaccine.

Vaccine Safety

Both the JYNNEOS and ACAM2000 vaccines are considered safe. The most common side effects of the JYNNEOS vaccine include pain, redness, and swelling at the injection site. The most common side effects of the ACAM2000 vaccine include fever, chills, and muscle aches.

How to Get Vaccinated

If you think you may be at risk for mpox, talk to your doctor about getting vaccinated. The mpox vaccine is available at many healthcare providers' offices, clinics, and pharmacies.

Additional Resources


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